ACD/Name Ranks Best of the Best According to Recently Published Study
Toronto, Canada (January 11, 2007)—
In a recent article published in the journal Molecules (2006, 11, 925-928), author Gernot A. Eller (Department of Drug Synthesis, Faculty of Life Sciences, University of Vienna) compared three 'state-of-the-art' nomenclature software tools, including Advanced Chemistry Development, Inc.'s, (ACD/Labs') ACD/Name 9.0, concluding that ACD/Name was the best option available for computerized systematic nomenclature.
The study uses a sampling of over 300 structures, taken from recently published journals, manually entered into each of the three software packages in order to evaluate their ability to generate acceptable (i.e., unambiguous) names as compared to manual nomenclature, and the quality of the unambiguous names generated. Under each criterion, ACD/Name showed significantly better results than the competitors, ChemDraw 10.0 (CambridgeSoft), and AutoNom 2000 (MDL), generating unambiguous names for 99% of structures tested, with 98% deemed to be 'preferred names'. In fact, in his article, the author states '...the quality of names that are generated from ACD/Name is second to none...'
A further study was conducted using only ACD/Name to examine its ability to generate names according to CAS nomenclature rules—neither of the other packages include this capability. The study concluded that the identical CAS names were generated by ACD/Name for 88% of the structures tested, while in the remaining 12%, about half of the names generated differed only slightly from the CAS name.
The study also provides a detailed comparison of the functional classes of molecules supported by each package. Once again, ACD/Name proved best with its ability to handle more complex structures, including those with fused ring systems, polymers, and some biochemicals—all capabilities lacking in the competitors offerings. The author also acknowledges that while version 10.0 of ACD/Name has since been released, the changes affect only complex functionality and that '...the basics seem to be absolutely mastered.'
Click here to read the full article and here for more information on ACD/Labs nomenclature products, ACD/Name 10.0 and ACD/Name Batch 10.0.
About Advanced Chemistry Development
Advanced Chemistry Development, Inc., (ACD/Labs) is a chemistry software company offering solutions that truly integrate chemical structures with analytical chemistry information to produce ChemAnalytics®. ACD/Labs creates innovative software packages that aid chemical research scientists worldwide with spectroscopic validation of structures, elucidation of unknown substances, chromatographic separation, medicinal chemistry, preformulation of novel drug agents, systematic nomenclature generation, and chemical patenting and publication. Combined, ACD/Labs' solutions create an analytical informatics system that provides dramatic feed-forward effects on the chemical and pharmaceutical research process. Founded in 1994, and headquartered in Toronto, Canada, ACD/Labs employs a team of over 145 dedicated individuals whose continual efforts carry ACD/Labs' innovative technologies into pharmaceutical, biotech, chemical, and materials companies throughout the world. Information about Advanced Chemistry Development and its products is available at www.acdlabs.com.
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