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Synthematix Integrates Arthur™ Suite with the Interactive Laboratory Tool, ACD/I-Lab

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Toronto, Canada, September 9, 2003 -

Synthematix, Inc., and Advanced Chemistry Development, Inc., (ACD/Labs) today announced the integration of Synthematix's Arthur™ Suite with the cutting-edge online prediction and search technology, ACD/I-Lab. As part of an ongoing agreement to integrate selected market-leading ACD/Labs solutions with Synthematix's Arthur Suite, the integration will address the enterprise-wide deployment of ACD/Labs prediction tools within the Arthur environment.

Synthematix's Arthur Suite is a comprehensive synthetic chemistry planning environment that enables chemists to build, search, model, and mine synthetic reactions and procedures within a chemistry-centric relational database. Using Synthematix's proprietary reaction planning system, chemists are able to design and record completely new experiments, or design around previous reactions and procedures found in the database.

Integrating Arthur Suite with ACD/Labs' Interactive Laboratory, ACD/I-Lab, will enable synthetic chemists to enhance their reaction data with a range of chemical properties. Arthur users will gain the capacity to predict the physicochemical properties of their molecular structures, predict the multinuclear NMR spectra of their reaction products, and generate chemical names, either IUPAC or CAS Index, to populate their databases with systematic nomenclature. "Synthematix and ACD/Labs are committed to providing our customers seamless integration of the software that they rely on in their day-to-day activities. Integrating ACD/I-Lab's market leading technology with Synthematix's reaction planning capabilities in the Arthur Suite places powerful, easy-to-use technology in the hands of every synthetic chemist in an organization. Tremendous research productivity and effectiveness gains are the net result to our customers," said Steve Jones, Synthematix CEO.

Antony Williams, V.P. of Scientific Development and Marketing at ACD/Labs, adds "We believe that ACD/I-Lab is the ideal enterprise deployment vehicle for our prediction and content database technologies. Integrating these capabilities with the Arthur Suite from Synthematix offers a best in breed combination which is second to none. It will address the needs of chemists to both manage their reaction data and predict or generate those properties associated with chemical structures in the database".

Previous integration between ACD/Labs and Synthematix enabled access to ACD/Labs prediction capabilities in the Arthur environment through ACD/Labs' standard desktop tools and batch predictors. Integration of Arthur with ACD/I-Lab will overcome the time and costs associated with deployment and maintenance of individual desktop modules, and increase the accessibility of prediction for Arthur users.

About Advanced Chemistry Development

Advanced Chemistry Development, Inc., (ACD/Labs) is a chemistry software company offering solutions that truly integrate chemical structures with analytical chemistry information to produce ChemAnalytics™. ACD/Labs creates innovative software packages that aid chemical research scientists worldwide with spectroscopic validation of structures, elucidation of unknown substances, chromatographic separation, medicinal chemistry, preformulation of novel drug agents, systematic nomenclature generation, and chemical patenting and publication. Combined, ACD/Labs' solutions create an analytical informatics system that provides dramatic feed-forward effects on the chemical and pharmaceutical research process. Founded in 1993, and headquartered in Toronto, Canada, ACD/Labs employs a team of over 100 dedicated individuals whose continual efforts carry ACD/Labs' innovative technologies into pharmaceutical, biotech, chemical, and materials companies throughout the world. Information about Advanced Chemistry Development and its products can be found at www.acdlabs.com.

About Synthematix

Synthematix, Inc. (http://www.synthematix.com), based in Research Triangle Park, NC, provides software for creating Comprehensive Chemistry Workflow Environments for synthetic chemists. Synthematix's products consist of the Arthur™ Suite of software and informatics products as well as the Synthematix SubstructureSearch™ technology. These products allow chemists to build, access and mine chemical databases with unprecedented power and flexibility. ARTHUR™ users include Cubist Pharmaceuticals, Incyte Corporation, Inspire Pharmaceuticals, Plexxikon Corporation, Sigma Aldrich and other leading chemistry organizations. These tools and databases increase the effectiveness and efficiency of research chemists while permitting enhanced access to a company's chemical R&D assets. Please visit www.synthematix.com for more information.

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