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Prediction of the Partition Coefficient:

Generic Parameters vs. System Training, Page 11


  1. Abstract
  2. How it works
  3. Why it works
  4. LogP Comparisons

  1. LogD Comparisons
  2. Discussion
  3. References
 
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VII. References

  1. Kurogi, Y.; Inoue, Y.; Tsutsumi, K.; Nakamura, S.; Nagao, K.; Yoshitsugu, H.; Tsuda, Y. Synthesis and hypolipidemic activities of novel 2-[4-[(diethoxyphosphoryl)methyl]phenyl] quinazolones and 4(3H)-quinazolinones J. Med. Chem. 1996, 39 (7), 1433-1437.
  2. Ward, P.; Armour, D. R.; Bays, D. E.; Evans, B.; Giblin, G. M. P.; Heron, N.; Hubbard, T.; Liang, K.; Middlemiss, D.; Mordaunt, J.; Naylor, A.; Pegg, N. A.; Vinader, V.; Watson, S. P.; Bountra, C., Evans, D. C. Discovery of an Orally Bioavailable NK1 Receptor Antagonist, (2S,3S)-(2-Methoxy-5-tetrazol-1-ylbenzyl) (2-phenylpiperidin-3-yl)amine (GR203040), with Potent Antiemetic Activity. J. Med. Chem. 1995, 38 (26), 4985-4992.
  3. Renau, T. E.; Sanchez, J. P.; Shapiro, M. A.; Dever, J. A.; Gracheck, J. A.; Domagala, J. A. J. Med. Chem. 1995, 38 (15), 2974-2977.
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