February 28 - March 4, 2005, Pittcon 2005, Orlando, FL, USA

A Global Collaboration for the Sharing of Liquid Chromatographic Column Information

Mike McBrien, Robin Martin, Patrik Petersson, Mel Euerby

Abstract

There are a huge number of high performance liquid chromatographic (HPLC) columns available on the market today. One of the main challenges with the development and selection of these columns has been the quantification of column performance in an effective manner. Tests need to be simple and universal, and results have to be easily communicated. In addition, there must be a quick and easy way to apply these results to the understanding of the effective selectivity of the materials.

In this paper, an effective evaluation system based on six column descriptors will be described, showing the practical application of the technology to column matching, orthogonal column selection, and targeted selectivity. The tests required to characterize the materials will be described as well as a web-based system for universal sharing of this data.

Download the presentation in MS PowerPoint (633 Kb ZIP file) or Adobe Acrobat format (399 Kb PDF file).

Relevant Products/Product Lines: Column Selector, ChromManager, Application Database, ChemSketch, ChromGenius Batch

Relevant Solution: Chromatographic Method Development