June 19, 2000. The presentation was given at the Wyndham Franklin Plaza, Philadelphia, Pensylvania, USA at High-Throughput Technologies Summit & Exposition

Spectroscopy Management for Screening of Combinatorial Libraries

Michael McBrien

Abstract

"Tubeless NMR" is the method of choice for the application of NMR to the analysis of combinatorial libraries. This technology leads to an inordinate amount of data requiring manual analysis. Software utilizing H1 NMR prediction algorithms can allow predicted spectra to be generated for each of the suggested library structures and a statistical analysis performed to determine matching. This can help to remove the bottleneck of data analysis.