Advanced Chemistry Development (ACD) develops software for the prediction
and optimization of chromatographic separations. This seminar will focus on
recent efforts around ACD's computer-assisted method development software,
Method Development Suite (MDS). The software is designed to help build a
chromatographic knowledge base, and then to take advantage of this knowledge
base by extension to new compounds. New additions to MDS including
Structure Similarity Search and Chromatographic Smart Search will be
discussed.
A great deal of interest has recently been given to generic, or "standard",
chromatographic methods. These methods are designed to be applied to a wide
variety of compounds, whether in support of custom method development,
parallel synthesis, or LCMS structure verification. ACD/ChromGenius is a
new ACD product designed to facilitate the implementation and interpretation
of standard methods using structure similarity algorithms along with
retention time prediction based on physicochemical parameters of compounds.
High-throughput strategies for selection between generic methods and
accurate structure verification will be discussed.
Presentations available:
